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KMID : 0882420070720000298
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Korean Journal of Medicine
2007 Volume.72 No. 0 p.298 ~ p.303
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A case of endobronchial metastasis from cervix cancer that was diagnosed by genotyping
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Shi Kyeh-Dong
Kim Joo-Young
Lee Ji-Hyun
Kim In-Ho
An Hee-Jung
Kim Eun-Kyung
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Abstract
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The lung is the most common site for metastasis from extrapulmonary malignancies. However, endobronchial metastases have rarely been reported. The major contributors include breast, colorectal and renal cell carcinoma. Endobronchial metastasis from cervix cancer is very rare and it is difficult to diagnose. It is defined as a bronchoscopically visible metastasis to the bronchus and it is histologically identical to cervix cancer. We experienced a case of endobronchial metastasis from cervix cancer, and this was pathologically confirmed by fiberoptic bronchoscopic biopsy. An 80-year-old woman was admitted to the hospital with chief complaints of cough and dyspnea. She was diagnosed as having cervix cancer two years ago. The bronchoscopic biopsy showed squamous cell carcinoma identical to the previously diagnosed cervix cancer. Human Papilloma Virus (HPV) genotyping from the specimen of the right middle lobar bronchus showed strongly positive high risk 16, which was identical to the HPV genotyping from the cervical brushing specimen. We report here on this case along with a literature review.(Korean J Med 72:S298-S303, 2007)
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KEYWORD
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Endobronchial metastasis, Cervix cancer
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